RAB29, member RAS oncogene familyGenealiases: RAB7L · RAB7L1
Q-omics provides the consensus-scored RAB29 profile across patient tissues and cancer cell-line models. RAB29 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RAB29 is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, RAB29 RNA expression shows 19,909 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, HNSC, and UVM as cancer lineages where RAB29 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RAB29 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RAB29 survival associations across molecular data types. RAB29 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (6) and mass-spec protein abundance (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RAB29 RNA expression–survival associations across cancer types. High RAB29 expression shows unfavorable associations in UCEC, UVM, LIHC and THYM, but favorable associations in KIRC and LUAD. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RAB29 RNA expression.
This table summarizes RAB29 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 6. The strongest signals are observed in HNSC for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for RAB29. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RAB29 shows lower tumor expression in KICH, THCA and KIRC and higher tumor expression in HNSC, LIHC and COAD. The HNSC box plot shows higher RAB29 RNA expression in tumor versus normal tissue (log2 FC = +1.765, t-test p < 0.001).
This table shows molecular features associated with RAB29 in patient tissues and cancer cell lines. In patient samples, RAB29 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, RAB29 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SOFT_TISSUE, while CRISPR and shRNA rows add functional-dependency signals in CNS and LARGE_INTESTINE.
