RAB29

Across TCGA pan-cancer cohorts, RAB29 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RAB29’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RAB29 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB29 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and THCA are the cancer types where RAB29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+1.765	<.001	12	view →
KICH	Female	II,III,IV	−3.697	<.001	10	view →
THCA	Male	III,IV	−1.234	<.001	10	view →
LIHC	Male	II,III,IV	+1.301	<.001	8	view →
KIRC	Male	All	−0.745	<.001	8	view →
COAD	All	II,III,IV	+0.553	<.001	6	view →
STAD	Male	II,III,IV	+1.007	<.001	5	view →
CHOL	All	All	+1.489	<.001	3	view →
KIRP	Male	All	−0.590	.014	2	view →
LUAD	All	III,IV	−0.469	.007	2	view →
BRCA	Female	All	−0.234	.013	2	view →
LUSC	Male	III,IV	−1.260	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RAB29–HNSC

Open the HNSC breakdown →