olfactory receptor family 4 subfamily C member 11Genealiases: OR11-136 · OR4C11P
Q-omics provides the consensus-scored OR4C11 profile across patient tissues and cancer cell-line models. OR4C11 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, OR4C11 is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, OR4C11 RNA expression shows 6,111 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight BRCA, and COAD as cancer lineages where OR4C11 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR4C11 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR4C11 survival associations across molecular data types. OR4C11 RNA expression shows survival associations in the most cancer types (6), followed by mutation status (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR4C11 RNA expression–survival associations across cancer types. High OR4C11 expression shows unfavorable associations in BRCA, LAML, LIHC, LGG, SKCM and PCPG. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .033). Together, the overview and detailed table identify BRCA as the clearest survival context for OR4C11 RNA expression.
This table summarizes OR4C11 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for OR4C11. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR4C11 shows higher tumor expression in BRCA. The BRCA box plot shows higher OR4C11 RNA expression in tumor versus normal tissue (log2 FC = +0.018, t-test p = .020).
This table shows molecular features associated with OR4C11 in patient tissues and cancer cell lines. In patient samples, OR4C11 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR4C11 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in LUNG_SCLC and SKIN.
