OR4C11

Across TCGA pan-cancer cohorts, OR4C11 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated OR4C11 data layer compared with 5 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR4C11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4C11 expression acts as an unfavorable survival marker.

BRCA, LIHC, and LAML are the cancer types where OR4C11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
LIHC	OS	Tertile	All	0.164	0.704	.025	18	view →
LAML	DFS	Tertile	All	0.193	0.588	.024	18	view →
LGG	DFS	Tertile	All	0.118	0.826	<.001	9	view →
SKCM	DFS	Tertile	All	0.198	0.757	.032	9	view →
PCPG	DFS	Tertile	All	0.754	0.943	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR4C11–BRCA (DFS)

Open the BRCA breakdown →