OR4C11

Across TCGA cell cohorts, OR4C11 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4C11-associated genes across cancer lineages are PROKR2, LAIR2, and OR5A2. Each is linked with OR4C11 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C11-to-partner and partner-to-OR4C11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROKR2 grouped by OR4C11-low versus OR4C11-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C11→partner) and Y-score (partner→OR4C11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PROKR2 →	+0.386	+3.977	.006	.005	3	1
LUNG_NSCLC_LUAD	LAIR2 →	+0.659	+4.215	.007	.002	3	1
LUNG_NSCLC_LUAD	OR5A2 →	+0.004	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	HNRNPCL3 →	+0.020	+4.093	.004	.004	3	1
STOMACH	SPAG11B →	+0.057	+4.285	<.001	.007	3	1
STOMACH	TEX26 →	+0.037	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PROKR2 by OR4C11 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →