OR4C11

Across TCGA patient cohorts, OR4C11 mutation is significantly associated with the RNA expression of many other genes, with 833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C11-associated genes across cancer lineages are AURKA, GAGE2E, and RNU6-21P. Each is linked with OR4C11 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C11-to-partner and partner-to-OR4C11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AURKA grouped by OR4C11-low versus OR4C11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C11→partner) and Y-score (partner→OR4C11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AURKA →	+0.869	+3.584	.004	.003	3	3
LUSC	GAGE2E →	+0.120	+2.667	<.001	.005	3	3
COAD	RNU6-21P →	+0.447	+5.142	<.001	.002	3	2
COAD	TOR1BP1 →	+0.294	+4.602	<.001	<.001	3	2
COAD	RN7SL503P →	+0.413	+3.541	.001	.007	3	2
COAD	RNU6-389P →	+0.408	+4.017	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 833 associations by consensus.

AURKA by OR4C11 expression — UCEC

Explore this box plot interactively →