Q-omics provides the consensus-scored MFRP profile across patient tissues and cancer cell-line models. MFRP expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, MFRP RNA expression shows 7,997 significant protein co-abundance associations, with the highest sampling consensus in CCRCC. Together, these results highlight KIRC, and CCRCC as cancer lineages where MFRP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MFRP survival associations across molecular data types. MFRP RNA expression shows survival associations in the most cancer types (3), followed by mutation status (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MFRP data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
Mutation	Kaplan–Meier	7	KICH (13)	view →
RNA	Kaplan–Meier	3	KIRC (108)	view →

This table ranks reproducible MFRP RNA expression–survival associations across cancer types. High MFRP expression shows unfavorable associations in KIRC, STAD and SARC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MFRP RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.127	0.806	<.001	108	view →
STAD	DFS	Tertile	All	0.451	0.713	.036	9	view →
SARC	DFS	Tertile	All	0.098	0.591	.010	9	view →

Pink = unfavorable, green = favorable. all 3 lineages →

MFRP-KIRC (OS)

Kaplan–Meier survival curve for MFRP RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MFRP in patient tissues and cancer cell lines. In patient samples, MFRP shows the broadest associations at the RNA and protein expression levels, with CCRCC recurring as the lineage with the largest associated feature set. In cancer cell lines, MFRP RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and BLOOD_Leukemia.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	7,997	CCRCC (3559)	view →
RNA	3,504	STAD (1563)	view →
▼Mutation
RNA	1,431	UCEC (1215)	view →
Protein (RPPA)	32	UCEC (32)	view →
▼Protein (mass-spec)
RNA	22	LSCC (22)	view →
Protein (mass-spec)	3	LSCC (3)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼CRISPR
RNA	1,871	BONE (461)	view →
CRISPR	1,752	UPPER_AERODIGESTIVE_TRACT (154)	view →
▼Mutation
Mutation	2,139	BLOOD_Leukemia (1900)	view →
RNA	28	BLOOD_Leukemia (12)	view →
▼RNA
RNA	1,856	UPPER_AERODIGESTIVE_TRACT (481)	view →
Function (RNA)	362	BLOOD_Leukemia (144)	view →