MFRP

Across TCGA patient cohorts, MFRP protein abundance is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MFRP-associated genes across cancer lineages are RNU6-29P, RHEBP1, and RNU6-919P. Each is linked with MFRP in more than 1 cancer types. Because this analysis shows association rather than direction, both MFRP-to-partner and partner-to-MFRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFRP versus RNU6-29P in LSCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFRP→partner) and Y-score (partner→MFRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNU6-29P →	+0.763	+2.868	<.001	.008	3	1
LSCC	RHEBP1 →	+0.180	+2.868	<.001	.008	3	1
LSCC	RNU6-919P →	+1.130	+2.868	.008	.008	3	1
LSCC	FRG2JP →	+0.485	+3.627	<.001	.009	3	1
LSCC	TTLL10 →	+0.463	+1.386	.001	.007	2	1
LSCC	MAGEB3 →	+0.045	+3.298	.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MFRP vs RNU6-29P — LSCC

Explore this scatter interactively →