MFRP

Across TCGA cell cohorts, MFRP RNA expression is significantly associated with the go_rna of many other GO terms, with 362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFRP-associated GO terms across cancer lineages are Protein depolymerization, Negative regulation of cation transmembrane transport, and Mitochondrial electron transport, succinate to ubiquinone. Each is linked with MFRP in more than 2 cancer types. Because this analysis shows association rather than direction, both MFRP-to-partner and partner-to-MFRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by MFRP-low versus MFRP-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFRP→partner) and Y-score (partner→MFRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein depolymerization →	+0.047	+0.061	.006	.007	3	3
LUNG_NSCLC_LUAD	Negative regulation of cation transmembrane transport →	-0.056	-0.004	.007	.001	3	3
LUNG_NSCLC_LUAD	Mitochondrial electron transport, succinate to ubiquinone →	+0.042	+0.004	.006	.009	3	3
KIDNEY	Regulation of protein localization to Cajal body →	+0.035	+0.004	.009	.009	3	3
KIDNEY	Positive regulation of protein localization to Cajal body →	+0.035	+0.004	.009	.009	3	3
BLOOD_Leukemia	GDF15-GFRAL signaling pathway →	-0.646	-0.042	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

Protein depolymerization by MFRP expression — BLOOD_Leukemia

Explore this box plot interactively →