HEPN1

Q-omics provides the consensus-scored HEPN1 profile across patient tissues and cancer cell-line models. HEPN1 expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, HEPN1 RNA expression shows 387 significant gene co-expression associations, with the highest sampling consensus in SCLC. Together, these results highlight SCLC as cancer lineages where HEPN1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes HEPN1 survival associations across molecular data types. HEPN1 RNA expression shows survival associations in the most cancer types (1), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HEPN1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
Mutation	Kaplan–Meier	3	SKCM (12)	view →
RNA	Kaplan–Meier	1	SCLC (9)	view →

This table ranks reproducible HEPN1 RNA expression–survival associations across cancer types. High HEPN1 expression shows unfavorable associations in SCLC. The SCLC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .017). Together, the overview and detailed table identify SCLC as the clearest survival context for HEPN1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Tertile	IV	0.110	0.414	.017	9	view →

Pink = unfavorable, green = favorable. all 1 lineages →

HEPN1-SCLC (DFS)

Explore this curve interactively →