Across TCGA patient cohorts, HEPN1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HEPN1-associated genes across cancer lineages are Adipocytes, Hepatocytes, and Sebocytes. Each is linked with HEPN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEPN1-to-partner and partner-to-HEPN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPN1→partner) and Y-score (partner→HEPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.029	+3.729	.007	.002	3	1
UCEC	Hepatocytes →	+0.017	+2.828	.009	.036	3	1
UCEC	Sebocytes →	+0.037	+2.828	.015	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

HEPN1 survival (RNA) · tumor vs normal (RNA) · all HEPN1 data types