Across TCGA patient cohorts, HEPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 179 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible HEPN1-associated GO terms across cancer lineages are Positive regulation of autophagy, Regulation of very-low-density lipoprotein particle remodeling, and Regulation of cell-substrate junction organization. Each is linked with HEPN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEPN1-to-partner and partner-to-HEPN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPN1→partner) and Y-score (partner→HEPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of autophagy →	+0.040	+0.077	.002	.001	3	1
SCLC	Regulation of very-low-density lipoprotein particle remodeling →	-0.125	-0.082	<.001	<.001	3	1
SCLC	Regulation of cell-substrate junction organization →	+0.092	+0.085	<.001	.004	3	1
SCLC	Purine nucleoside transmembrane transport →	-0.641	-0.083	.002	.001	3	1
SCLC	Endosomal transport →	+0.052	+0.065	<.001	<.001	3	1
SCLC	Regulation of macroautophagy →	+0.053	+0.076	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 179 associations by consensus.

Exploration

HEPN1 survival (RNA) · tumor vs normal (RNA) · all HEPN1 data types