Q-omics provides the consensus-scored CCDC28A-AS1 profile across patient tissues and cancer cell-line models. CCDC28A-AS1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in LGG. Among the 18 cancer types available for tumor–normal comparison, CCDC28A-AS1 is differentially expressed in 13, with the highest sampling consensus in KICH. Additionally, CCDC28A-AS1 RNA expression shows 18,388 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight LGG, KICH, and UVM as cancer lineages where CCDC28A-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CCDC28A-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CCDC28A-AS1 survival associations across molecular data types. CCDC28A-AS1 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CCDC28A-AS1 RNA expression–survival associations across cancer types. High CCDC28A-AS1 expression shows unfavorable associations in LGG, ACC, KIRC and COAD, but favorable associations in UCS and BLCA. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LGG as the clearest survival context for CCDC28A-AS1 RNA expression.
This table summarizes CCDC28A-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for CCDC28A-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CCDC28A-AS1 shows lower tumor expression in KICH, THCA and KIRC and higher tumor expression in BLCA, LUSC and COAD. The KICH box plot shows higher CCDC28A-AS1 RNA expression in normal versus tumor tissue (log2 FC = −0.407, t-test p < 0.001).
This table shows molecular features associated with CCDC28A-AS1 in patient tissues and cancer cell lines. In patient samples, CCDC28A-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, CCDC28A-AS1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in PANCREAS.
