CCDC28A-AS1

Across TCGA patient cohorts, CCDC28A-AS1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC28A-AS1-associated genes across cancer lineages are MIR494, RNA5SP305, and RNU4-58P. Each is linked with CCDC28A-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC28A-AS1-to-partner and partner-to-CCDC28A-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR494 grouped by CCDC28A-AS1-low versus CCDC28A-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A-AS1→partner) and Y-score (partner→CCDC28A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR494 →	+0.738	+6.722	<.001	<.001	3	1
UCEC	RNA5SP305 →	+1.036	+5.081	<.001	.008	3	1
UCEC	RNU4-58P →	+0.497	+5.133	.001	.008	3	1
UCEC	RNU6-806P →	+0.869	+6.335	<.001	.001	3	1
UCEC	RNU6-364P →	+0.848	+5.771	<.001	.003	3	1
UCEC	MIR1302-7 →	+1.041	+6.123	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

MIR494 by CCDC28A-AS1 expression — UCEC

Explore this box plot interactively →