CCDC28A-AS1

Across TCGA pan-cancer cohorts, CCDC28A-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CCDC28A-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher CCDC28A-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC28A-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

LGG, ACC, and UCS are the cancer types where CCDC28A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.749	0.866	<.001	49	view →
ACC	DFS	Median	All	0.434	0.724	.001	48	view →
UCS	DFS	Tertile	III,IV	0.554	0.089	.001	44	view →
KIRC	DFS	Tertile	II,III,IV	0.434	0.650	.001	42	view →
BLCA	OS	Tertile	All	0.585	0.339	.001	33	view →
COAD	DFS	Quartile	III,IV	0.263	0.512	.004	28	view →
MESO	OS	Median	All	0.300	0.465	.007	26	view →
THYM	DFS	Tertile	All	0.803	0.526	.002	25	view →
READ	DFS	Median	All	0.753	0.269	.005	17	view →
SKCM	OS	Tertile	IV	0.813	0.384	.001	14	view →
LUAD	DFS	Median	All	0.830	0.710	.006	12	view →
CESC	OS	Tertile	II,III,IV	0.900	0.713	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CCDC28A-AS1–LGG (OS)

Open the LGG breakdown →