CCDC28A-AS1

Across TCGA pan-cancer cohorts, CCDC28A-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CCDC28A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CCDC28A-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC28A-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and BLCA are the cancer types where CCDC28A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC28A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−0.407	<.001	10	view →
THCA	Male	IV	−0.556	<.001	9	view →
BLCA	All	All	+0.365	.003	7	view →
LUSC	Female	All	+0.612	<.001	6	view →
COAD	All	All	+0.164	.001	6	view →
KIRC	All	II,III,IV	−0.091	.001	6	view →
HNSC	Male	III,IV	+0.239	.006	5	view →
STAD	Male	All	+0.203	<.001	4	view →
LIHC	All	All	+0.099	.008	4	view →
READ	All	All	+0.365	.005	2	view →
PRAD	All	All	+0.293	<.001	2	view →
UCEC	All	All	+0.259	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CCDC28A-AS1–KICH

Open the KICH breakdown →