Q-omics provides the consensus-scored ZFP41 profile across patient tissues and cancer cell-line models. ZFP41 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, ZFP41 is differentially expressed in 14, with the highest sampling consensus in HNSC. Additionally, ZFP41 RNA expression shows 20,275 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight LIHC, HNSC, and ACC as cancer lineages where ZFP41 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZFP41 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZFP41 survival associations across molecular data types. ZFP41 RNA expression shows survival associations in the most cancer types (23), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZFP41 RNA expression–survival associations across cancer types. High ZFP41 expression shows unfavorable associations in LIHC, UVM, SKCM, BLCA, ACC and LUAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for ZFP41 RNA expression.
This table summarizes ZFP41 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for ZFP41. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZFP41 shows higher tumor expression in HNSC, COAD, LIHC, LUAD, STAD and LUSC. The HNSC box plot shows higher ZFP41 RNA expression in tumor versus normal tissue (log2 FC = +1.091, t-test p < 0.001).
This table shows molecular features associated with ZFP41 in patient tissues and cancer cell lines. In patient samples, ZFP41 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, ZFP41 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LIVER, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and BLOOD_Lymphoma.
