ZFP41

Across TCGA patient cohorts, ZFP41 mutation is significantly associated with the RNA expression of many other genes, with 1,623 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP41-associated genes across cancer lineages are RN7SKP221, RN7SL802P, and USP17L15. Each is linked with ZFP41 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP41-to-partner and partner-to-ZFP41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP221 grouped by ZFP41-low versus ZFP41-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP41→partner) and Y-score (partner→ZFP41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	3
COAD	RN7SL802P →	+0.565	+5.721	<.001	.001	3	3
LUSC	USP17L15 →	+0.019	+7.924	<.001	.008	3	2
SKCM	DGCR6L →	+0.494	+2.770	.008	.003	3	2
SKCM	JADE2 →	+0.803	+2.719	<.001	.003	3	2
COAD	RNU6-650P →	+0.431	+5.392	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,623 associations by consensus.

RN7SKP221 by ZFP41 expression — BRCA

Explore this box plot interactively →