ZFP41

Across TCGA pan-cancer cohorts, ZFP41 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZFP41 data layer compared with 1 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ZFP41 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZFP41 expression acts as an unfavorable survival marker, although some lineages such as UCEC and KIRC show a favorable association.

LIHC, UVM, and SKCM are the cancer types where ZFP41 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.410	0.588	<.001	99	view →
UVM	OS	Median	III,IV	0.245	0.836	.002	65	view →
SKCM	OS	Quartile	All	0.797	0.897	.002	33	view →
BLCA	DFS	Quartile	All	0.274	0.492	.008	22	view →
ACC	DFS	Quartile	All	0.241	0.750	<.001	21	view →
LUAD	DFS	Median	IV	0.272	0.804	.006	21	view →
UCEC	DFS	Tertile	IV	0.892	0.636	.015	20	view →
KIRC	DFS	Tertile	All	0.764	0.482	<.001	20	view →
MESO	DFS	Quartile	IV	0.175	0.739	.006	18	view →
PRAD	DFS	Quartile	All	0.689	0.865	.002	18	view →
SCLC	OS	Tertile	II,III,IV	1.000	0.247	.006	16	view →
KICH	OS	Quartile	III,IV	0.125	0.913	.017	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZFP41–LIHC (OS)

Open the LIHC breakdown →