TTC26

Across TCGA patient cohorts, TTC26 mutation is significantly associated with the RNA expression of many other genes, with 3,191 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC26-associated genes across cancer lineages are ABCD1P3, MIR548AL, and RN7SL248P. Each is linked with TTC26 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC26-to-partner and partner-to-TTC26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCD1P3 grouped by TTC26-low versus TTC26-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC26→partner) and Y-score (partner→TTC26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ABCD1P3 →	+0.063	+4.625	<.001	.008	3	3
SKCM	MIR548AL →	+0.320	+4.897	<.001	.002	3	2
UCEC	RN7SL248P →	+0.044	+2.783	<.001	.009	3	2
UCEC	RNU4-82P →	+0.299	+1.729	.001	.002	3	2
UCEC	RNU6-23P →	+0.283	+1.797	<.001	.005	3	2
UCEC	TRAJ57 →	+0.311	+1.878	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,191 associations by consensus.

ABCD1P3 by TTC26 expression — LUSC

Explore this box plot interactively →