Q-omics provides the consensus-scored MIR548AL profile across patient tissues and cancer cell-line models. MIR548AL expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, MIR548AL is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, MIR548AL RNA expression shows 5,725 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, THCA, and STAD as cancer lineages where MIR548AL shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR548AL — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR548AL survival associations across molecular data types. MIR548AL RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR548AL RNA expression–survival associations across cancer types. High MIR548AL expression shows unfavorable associations in KICH, CHOL, KIRC, BRCA, LGG and KIRP. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for MIR548AL RNA expression.
This table summarizes MIR548AL tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR548AL. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR548AL shows lower tumor expression in THCA. The THCA box plot shows higher MIR548AL RNA expression in normal versus tumor tissue (log2 FC = −0.243, t-test p = .001).
This table shows molecular features associated with MIR548AL in patient tissues and cancer cell lines. In patient samples, MIR548AL shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
