TTC26

Across TCGA pan-cancer cohorts, TTC26 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TTC26’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TTC26 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TTC26 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, THCA, and KIRP are the cancer types where TTC26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTC26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.577	<.001	11	view →
THCA	Male	II,III,IV	−0.644	<.001	10	view →
KIRP	Male	II,III,IV	+1.135	<.001	9	view →
BLCA	Female	All	+0.940	<.001	9	view →
STAD	All	II,III,IV	+0.772	<.001	9	view →
KICH	Female	II,III,IV	−1.958	<.001	8	view →
HNSC	Male	IV	+1.250	<.001	8	view →
LIHC	Male	All	+0.659	<.001	8	view →
READ	All	All	+1.036	.005	6	view →
BRCA	All	III,IV	+0.824	<.001	6	view →
CHOL	Male	All	+2.038	<.001	5	view →
KIRC	All	All	+0.228	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TTC26–COAD

Open the COAD breakdown →