Q-omics provides the consensus-scored TCF24 profile across patient tissues and cancer cell-line models. TCF24 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, TCF24 is differentially expressed in 16, with the highest sampling consensus in KIRC. Additionally, TCF24 RNA expression shows 15,329 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight THCA, KIRC, and THYM as cancer lineages where TCF24 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TCF24 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TCF24 survival associations across molecular data types. TCF24 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TCF24 RNA expression–survival associations across cancer types. High TCF24 expression shows unfavorable associations in THCA, KIRC, LGG and KICH, but favorable associations in SCLC and LUSC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for TCF24 RNA expression.
This table summarizes TCF24 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TCF24. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TCF24 shows lower tumor expression in KIRC and KIRP and higher tumor expression in BLCA, HNSC, COAD and LUSC. The KIRC box plot shows higher TCF24 RNA expression in normal versus tumor tissue (log2 FC = −0.894, t-test p < 0.001).
This table shows molecular features associated with TCF24 in patient tissues and cancer cell lines. In patient samples, TCF24 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, TCF24 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in BONE and UPPER_AERODIGESTIVE_TRACT.
