TCF24

Across TCGA pan-cancer cohorts, TCF24 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TCF24 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher TCF24 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TCF24 expression acts as an unfavorable survival marker, although some lineages such as SCLC and LUSC show a favorable association.

THCA, SCLC, and KIRC are the cancer types where TCF24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.714	0.868	<.001	95	view →
SCLC	OS	Median	All	0.429	0.122	<.001	76	view →
KIRC	OS	Quartile	All	0.724	0.850	<.001	64	view →
LUSC	OS	Median	All	0.821	0.701	<.001	57	view →
LGG	DFS	Median	All	0.633	0.842	<.001	51	view →
KICH	OS	Quartile	II,III,IV	0.692	0.968	.001	36	view →
BRCA	DFS	Tertile	IV	0.873	0.262	<.001	32	view →
STAD	DFS	Tertile	II,III,IV	0.458	0.614	.008	29	view →
LIHC	OS	Quartile	All	0.640	0.808	<.001	28	view →
SARC	OS	Median	All	0.667	0.817	<.001	26	view →
READ	OS	Median	All	0.893	0.747	.008	17	view →
KIRP	DFS	Tertile	IV	0.904	0.603	.024	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TCF24–THCA (DFS)

Open the THCA breakdown →