SLC7A6OS

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC7A6OS mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SLC7A6OS-associated genes across cancer lineages are MIR3689B, RN7SL210P, and NPAP1L. Each is linked with SLC7A6OS in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A6OS-to-partner and partner-to-SLC7A6OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3689B grouped by SLC7A6OS-low versus SLC7A6OS-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A6OS→partner) and Y-score (partner→SLC7A6OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMIR3689B →+0.315+6.309<.001.00132
BRCARN7SL210P →+0.214+5.070.004.00831
BRCANPAP1L →+0.150+5.441<.001.00531
HNSCLINC01669 →+0.024+5.303<.001.00631
BRCARNU6-1049P →+0.248+6.711.004<.00131
BRCATP53TG3GP →+0.672+5.646<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

MIR3689B by SLC7A6OS expression — LUSC

Box plot of MIR3689B in SLC7A6OS-low vs SLC7A6OS-high samples in LUSC.

Explore this box plot interactively →

Exploration