SLC7A6OS

Across TCGA pan-cancer cohorts, SLC7A6OS RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SLC7A6OS data layer compared with 3 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SLC7A6OS RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC7A6OS expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

CESC, LUSC, and KIRC are the cancer types where SLC7A6OS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	III,IV	0.209	0.882	<.001	72	view →
LUSC	OS	Quartile	III,IV	0.540	0.836	.001	60	view →
KIRC	DFS	Tertile	All	0.779	0.490	<.001	56	view →
LIHC	DFS	Median	All	0.471	0.611	.001	45	view →
HNSC	OS	Tertile	All	0.706	0.801	.003	43	view →
UCS	DFS	Tertile	IV	0.996	0.484	.024	34	view →
LUAD	OS	Quartile	II,III,IV	0.862	0.659	.011	29	view →
COAD	DFS	Median	All	0.359	0.706	.005	27	view →
ACC	DFS	Quartile	All	0.306	0.707	.010	25	view →
SCLC	OS	Tertile	III,IV	0.838	0.360	.004	25	view →
THYM	DFS	Median	II,III,IV	0.859	0.590	.016	23	view →
BLCA	DFS	Quartile	All	0.473	0.745	.003	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SLC7A6OS–CESC (DFS)

Open the CESC breakdown →