SLC7A6OS

Across TCGA pan-cancer cohorts, SLC7A6OS RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC7A6OS’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC7A6OS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC7A6OS is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

HNSC, KIRP, and COAD are the cancer types where SLC7A6OS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC7A6OS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+0.977	<.001	12	view →
KIRP	All	II,III,IV	+0.675	<.001	11	view →
COAD	All	III,IV	+0.576	<.001	11	view →
THCA	All	II,III,IV	−0.492	<.001	9	view →
BLCA	All	All	+0.550	<.001	8	view →
LIHC	All	II,III,IV	+0.450	<.001	7	view →
STAD	Male	II,III,IV	+0.588	.001	6	view →
KIRC	All	All	+0.230	<.001	6	view →
BRCA	Female	All	−0.158	.003	6	view →
LUAD	Male	All	+0.391	<.001	5	view →
CHOL	Male	All	+1.390	<.001	4	view →
LUSC	Male	All	+0.407	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC7A6OS–HNSC

Open the HNSC breakdown →