nuclear pore associated protein 1 like (pseudogene)Genealiases: []
Q-omics provides the consensus-scored NPAP1L profile across patient tissues and cancer cell-line models. NPAP1L expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, NPAP1L is differentially expressed in 2, with the highest sampling consensus in HNSC. Additionally, NPAP1L RNA expression shows 6,408 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight COAD, HNSC, and TGCT as cancer lineages where NPAP1L shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NPAP1L — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NPAP1L survival associations across molecular data types. NPAP1L RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NPAP1L RNA expression–survival associations across cancer types. High NPAP1L expression shows unfavorable associations in COAD, KICH, UCEC, THCA, DLBC and LIHC. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for NPAP1L RNA expression.
This table summarizes NPAP1L tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for NPAP1L. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NPAP1L shows higher tumor expression in HNSC and LUSC. The HNSC box plot shows higher NPAP1L RNA expression in tumor versus normal tissue (log2 FC = +0.061, t-test p < 0.001).
This table shows molecular features associated with NPAP1L in patient tissues and cancer cell lines. In patient samples, NPAP1L shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
