NPAP1L

Across TCGA pan-cancer cohorts, NPAP1L RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NPAP1L data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NPAP1L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NPAP1L expression acts as an unfavorable survival marker, although some lineages such as STAD and SKCM show a favorable association.

COAD, KICH, and UCEC are the cancer types where NPAP1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.342	0.789	<.001	126	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
UCEC	OS	Tertile	All	0.706	0.882	<.001	54	view →
THCA	OS	Tertile	All	0.171	0.929	<.001	39	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	28	view →
LIHC	OS	Tertile	All	0.153	0.780	<.001	18	view →
HNSC	OS	Tertile	III,IV	0.342	0.583	.039	12	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	12	view →
STAD	OS	Tertile	IV	0.642	0.203	.006	9	view →
GBM	OS	Tertile	All	0.167	0.423	.007	9	view →
PCPG	DFS	Tertile	All	0.535	0.935	.021	9	view →
SKCM	OS	Tertile	All	0.607	0.342	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NPAP1L–COAD (DFS)

Open the COAD breakdown →