SLC1A5

Across TCGA patient cohorts, SLC1A5 mutation is significantly associated with the RNA expression of many other genes, with 651 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC1A5-associated genes across cancer lineages are CFTRP3, KATNAL2, and UPP1. Each is linked with SLC1A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A5-to-partner and partner-to-SLC1A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFTRP3 grouped by SLC1A5-low versus SLC1A5-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A5→partner) and Y-score (partner→SLC1A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CFTRP3 →	+0.185	+4.912	<.001	.005	3	2
UCEC	KATNAL2 →	-0.728	-2.684	<.001	.006	3	2
UCEC	UPP1 →	+0.828	+3.169	<.001	<.001	3	2
UCEC	HOXC-AS1 →	+0.837	+2.230	.001	.002	3	2
UCEC	MNX1 →	+0.865	+2.513	.001	.001	3	2
PRAD	RNU6-1144P →	+0.383	+7.939	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 651 associations by consensus.

CFTRP3 by SLC1A5 expression — HNSC

Explore this box plot interactively →