olfactory receptor family 1 subfamily Q member 1Genealiases: HSTPCR106 · OR1Q2 · OR1Q3 · OR9-25 · OR9-A · OST226
Q-omics provides the consensus-scored OR1Q1 profile across patient tissues and cancer cell-line models. OR1Q1 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, OR1Q1 is differentially expressed in 7, with the highest sampling consensus in HNSC. Additionally, OR1Q1 RNA expression shows 10,089 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, HNSC, and THYM as cancer lineages where OR1Q1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR1Q1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR1Q1 survival associations across molecular data types. OR1Q1 RNA expression shows survival associations in the most cancer types (20), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR1Q1 RNA expression–survival associations across cancer types. High OR1Q1 expression shows unfavorable associations in KIRC, LIHC, ACC, LUSC and CESC, but favorable associations in SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for OR1Q1 RNA expression.
This table summarizes OR1Q1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for OR1Q1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR1Q1 shows lower tumor expression in BRCA and higher tumor expression in HNSC, STAD, LUSC, KIRC and LIHC. The HNSC box plot shows higher OR1Q1 RNA expression in tumor versus normal tissue (log2 FC = +0.059, t-test p = .003).
This table shows molecular features associated with OR1Q1 in patient tissues and cancer cell lines. In patient samples, OR1Q1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, OR1Q1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in URINARY_TRACT, while CRISPR and shRNA rows add functional-dependency signals in LARGE_INTESTINE and SKIN.
