OR1Q1

Across TCGA pan-cancer cohorts, OR1Q1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR1Q1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher OR1Q1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR1Q1 expression acts as an unfavorable survival marker.

STAD, LUAD, and LUSC are the cancer types where OR1Q1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.001	0.660	<.001	18	view →
LUAD	OS	Median	All	0.323	0.834	.003	6	view →
LUSC	OS	Median	All	0.176	0.724	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

OR1Q1–STAD (OS)

Open the STAD breakdown →