OR1Q1

Across TCGA cell cohorts, OR1Q1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR1Q1-associated genes across cancer lineages are FAM71C, PRORY, and RGS21. Each is linked with OR1Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1Q1-to-partner and partner-to-OR1Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM71C grouped by OR1Q1-low versus OR1Q1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1Q1→partner) and Y-score (partner→OR1Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM71C →	+0.015	+4.095	.001	.009	3	1
SKIN	PRORY →	+0.596	+4.273	.005	.006	3	1
BLOOD_Leukemia	RGS21 →	+0.059	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM71C by OR1Q1 expression — SKIN

Explore this box plot interactively →