OR1Q1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR1Q1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR1Q1-associated genes across cancer lineages are Endothelial cells, Skeletal muscle, and GMP. Each is linked with OR1Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1Q1-to-partner and partner-to-OR1Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by OR1Q1-low versus OR1Q1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1Q1→partner) and Y-score (partner→OR1Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMEndothelial cells →-0.027-3.144.045.01831
SKCMSkeletal muscle →+0.028+1.743.031.00431
LUSCGMP →+0.054+4.264.010.02431
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by OR1Q1 expression — SKCM

Box plot of Endothelial cells in OR1Q1-low vs OR1Q1-high samples in SKCM.

Explore this box plot interactively →

Exploration