Q-omics provides the consensus-scored OR1A1 profile across patient tissues and cancer cell-line models. OR1A1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, OR1A1 RNA expression shows 6,119 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SCLC, and STAD as cancer lineages where OR1A1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR1A1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR1A1 survival associations across molecular data types. OR1A1 RNA expression shows survival associations in the most cancer types (10), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR1A1 RNA expression–survival associations across cancer types. High OR1A1 expression shows unfavorable associations in SCLC, MESO, DLBC and THCA, but favorable associations in STAD and ESCA. The SCLC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SCLC as the clearest survival context for OR1A1 RNA expression.
This table shows molecular features associated with OR1A1 in patient tissues and cancer cell lines. In patient samples, OR1A1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR1A1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in LARGE_INTESTINE and KIDNEY.
