OR1A1

Across TCGA patient cohorts, OR1A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,119 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR1A1-associated GO terms across cancer lineages are Methylation, Glucose metabolic process, and Regulation of DNA repair. Each is linked with OR1A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both OR1A1-to-partner and partner-to-OR1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by OR1A1-low versus OR1A1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1A1→partner) and Y-score (partner→OR1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.091	+0.114	<.001	<.001	3	8
STAD	Glucose metabolic process →	+0.095	+0.091	<.001	<.001	3	7
STAD	Regulation of DNA repair →	+0.100	+0.100	<.001	<.001	3	7
STAD	tRNA metabolic process →	+0.104	+0.100	<.001	<.001	3	7
STAD	Cellular modified amino acid metabolic process →	+0.064	+0.100	<.001	<.001	3	7
STAD	Nucleoside triphosphate metabolic process →	+0.111	+0.099	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,119 associations by consensus.

Methylation by OR1A1 expression — STAD

Explore this box plot interactively →