OR1A1

Across TCGA cell cohorts, OR1A1 RNA expression is significantly associated with the mutation status of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR1A1-associated genes across cancer lineages are ATR, SIPA1L3, and SMYD1. Each is linked with OR1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1A1-to-partner and partner-to-OR1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATR grouped by OR1A1-low versus OR1A1-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1A1→partner) and Y-score (partner→OR1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ATR →	+3.209	+0.003	.004	<.001	3	2
SOFT_TISSUE	SIPA1L3 →	+4.392	+0.008	.004	<.001	3	1
SOFT_TISSUE	SMYD1 →	+4.392	+0.008	.004	<.001	3	1
SOFT_TISSUE	PARP10 →	+5.977	+0.013	.001	<.001	3	1
SOFT_TISSUE	UNC5C →	+5.977	+0.013	.001	<.001	3	1
BLOOD_Myeloma	AKAP6 →	+4.807	+0.413	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

ATR by OR1A1 expression — BLOOD_Lymphoma

Explore this box plot interactively →