MKS1

Across TCGA patient cohorts, MKS1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,688 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MKS1-associated genes across cancer lineages are CFAP69, DNALI1, and TTC21A. Each is linked with MKS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MKS1-to-partner and partner-to-MKS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKS1 versus CFAP69 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKS1→partner) and Y-score (partner→MKS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CFAP69 →	+1.078	+0.385	<.001	<.001	3	3
BRCA	DNALI1 →	+2.781	+0.510	<.001	<.001	3	3
UCEC	TTC21A →	+1.032	+0.606	.001	.001	3	3
BRCA	TMEM26 →	+1.648	+0.402	<.001	<.001	3	3
BRCA	GIHCG →	+1.120	+0.476	<.001	.001	3	3
CCRCC	MMD →	+0.885	+0.565	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,688 associations by consensus.

MKS1 vs CFAP69 — BRCA

Explore this scatter interactively →