cilia and flagella associated protein 69Genealiases: C7orf63 · FAP69 · SPGF24
Q-omics provides the consensus-scored CFAP69 profile across patient tissues and cancer cell-line models. CFAP69 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, CFAP69 is differentially expressed in 8, with the highest sampling consensus in KICH. Additionally, CFAP69 RNA expression shows 19,314 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight BLCA, KICH, and THYM as cancer lineages where CFAP69 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CFAP69 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CFAP69 survival associations across molecular data types. CFAP69 RNA expression shows survival associations in the most cancer types (19), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CFAP69 RNA expression–survival associations across cancer types. High CFAP69 expression shows unfavorable associations in LUSC, LGG and KICH, but favorable associations in BLCA, BRCA and MESO. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for CFAP69 RNA expression.
This table summarizes CFAP69 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for CFAP69. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CFAP69 shows lower tumor expression in KICH, THCA, LUSC and BRCA and higher tumor expression in COAD and CHOL. The KICH box plot shows higher CFAP69 RNA expression in normal versus tumor tissue (log2 FC = −1.451, t-test p < 0.001).
This table shows molecular features associated with CFAP69 in patient tissues and cancer cell lines. In patient samples, CFAP69 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, CFAP69 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUSC, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and CNS.
