CFAP69

Across TCGA patient cohorts, CFAP69 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP69-associated genes across cancer lineages are XBP1, Fibronectin, and eIF4E. Each is linked with CFAP69 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP69-to-partner and partner-to-CFAP69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XBP1 grouped by CFAP69-low versus CFAP69-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP69→partner) and Y-score (partner→CFAP69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	XBP1 →	-0.253	-3.700	.025	.001	3	3
SKCM	Fibronectin →	-0.495	-3.000	.017	.035	3	2
UCEC	eIF4E →	+0.147	+1.716	.032	.003	3	2
UCEC	A-Raf_pS299 →	-0.080	-1.807	.037	.025	3	2
UCEC	JNK2 →	+0.186	+1.459	.003	.012	3	2
UCEC	MEK1 →	+0.432	+2.736	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

XBP1 by CFAP69 expression — SKCM

Explore this box plot interactively →