LCE2C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCE2C mutation is significantly associated with the RNA expression of many other genes, with 322 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE2C-associated genes across cancer lineages are KHDC3L, RNU7-80P, and RN7SL791P. Each is linked with LCE2C in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2C-to-partner and partner-to-LCE2C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2C→partner) and Y-score (partner→LCE2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADKHDC3L →+0.073+3.843<.001.00432
COADRNU7-80P →+0.708+4.893.003<.00132
COADRN7SL791P →+0.394+4.893<.001<.00132
SKCMSPRYD7P1 →+0.085+4.867<.001.00532
SKCMRNU7-175P →+0.690+4.913<.001.00232
SKCMRNU6-1020P →+0.251+4.513<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 322 associations by consensus.

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