Q-omics provides the consensus-scored RNU7-80P profile across patient tissues and cancer cell-line models. RNU7-80P expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RNU7-80P is differentially expressed in 2, with the highest sampling consensus in ESCA. Additionally, RNU7-80P RNA expression shows 8,362 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight KIRP, ESCA, and COAD as cancer lineages where RNU7-80P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU7-80P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU7-80P survival associations across molecular data types. RNU7-80P RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU7-80P RNA expression–survival associations across cancer types. High RNU7-80P expression shows unfavorable associations in KIRP, BRCA, THCA, READ and STAD, but favorable associations in HNSC. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for RNU7-80P RNA expression.
This table summarizes RNU7-80P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in ESCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU7-80P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU7-80P shows lower tumor expression in LUSC and higher tumor expression in ESCA. The ESCA box plot shows higher RNU7-80P RNA expression in tumor versus normal tissue (log2 FC = +0.735, t-test p = .016).
This table shows molecular features associated with RNU7-80P in patient tissues and cancer cell lines. In patient samples, RNU7-80P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
