RNU7-80P

Across TCGA pan-cancer cohorts, RNU7-80P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU7-80P’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RNU7-80P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-80P is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

ESCA and LUSC are the cancer types where RNU7-80P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-80P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.735	.016	2	view →
LUSC	All	All	−0.087	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNU7-80P–ESCA

Open the ESCA breakdown →