Q-omics provides the consensus-scored SPRYD7P1 profile across patient tissues and cancer cell-line models. SPRYD7P1 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, SPRYD7P1 RNA expression shows 6,126 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BRCA, and STAD as cancer lineages where SPRYD7P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SPRYD7P1 survival associations across molecular data types. SPRYD7P1 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SPRYD7P1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	BRCA (54)	view →

This table ranks reproducible SPRYD7P1 RNA expression–survival associations across cancer types. High SPRYD7P1 expression shows unfavorable associations in BRCA, SKCM, UCS, LUAD and KIRP, but favorable associations in OV. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .023). Together, the overview and detailed table identify BRCA as the clearest survival context for SPRYD7P1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	II,III,IV	0.829	0.944	.023	54	view →
SKCM	OS	Tertile	III,IV	0.179	0.801	<.001	48	view →
OV	OS	Tertile	II,III,IV	0.991	0.684	.031	24	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
LUAD	OS	Tertile	II,III,IV	0.141	0.677	.002	18	view →
KIRP	OS	Tertile	All	0.280	0.716	.002	9	view →

Pink = unfavorable, green = favorable. all 7 lineages →

SPRYD7P1-BRCA (DFS)

Kaplan–Meier survival curve for SPRYD7P1 RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SPRYD7P1 in patient tissues and cancer cell lines. In patient samples, SPRYD7P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,126	STAD (5869)	view →
RNA	4,873	STAD (1274)	view →