Q-omics provides the consensus-scored KRTAP22-1 profile across patient tissues and cancer cell-line models. KRTAP22-1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, KRTAP22-1 RNA expression shows 8,169 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight UCEC, and COAD as cancer lineages where KRTAP22-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KRTAP22-1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KRTAP22-1 survival associations across molecular data types. KRTAP22-1 RNA expression shows survival associations in the most cancer types (10), followed by mutation status (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KRTAP22-1 RNA expression–survival associations across cancer types. High KRTAP22-1 expression shows unfavorable associations in UCEC, HNSC, SKCM, SARC, LIHC and BLCA. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for KRTAP22-1 RNA expression.
This table shows molecular features associated with KRTAP22-1 in patient tissues and cancer cell lines. In patient samples, KRTAP22-1 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set. In cancer cell lines, KRTAP22-1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in URINARY_TRACT and BLOOD_Myeloma.
