Across TCGA patient cohorts, KRTAP22-1 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KRTAP22-1-associated genes across cancer lineages are RPL35AP15, KRTAP12-6P, and MIR5591. Each is linked with KRTAP22-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP22-1-to-partner and partner-to-KRTAP22-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP22-1→partner) and Y-score (partner→KRTAP22-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL35AP15 →	+0.228	+4.038	<.001	.004	3	2
COAD	KRTAP12-6P →	+1.060	+5.212	<.001	.007	3	2
BLCA	MIR5591 →	+0.420	+7.640	<.001	.009	3	1
UCEC	NAPGP2 →	+0.102	+4.267	.005	.009	3	1
COAD	KRTAP10-8 →	+0.554	+5.790	<.001	.003	3	1
COAD	OR10G6 →	+0.209	+5.893	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

KRTAP22-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP22-1 data types