Across TCGA patient cohorts, KRTAP20-2 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP20-2-associated genes across cancer lineages are RN7SL726P, MIR6129, and MIR6133. Each is linked with KRTAP20-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP20-2-to-partner and partner-to-KRTAP20-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP20-2→partner) and Y-score (partner→KRTAP20-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL726P →	+0.301	+4.488	<.001	<.001	3	1
UCEC	MIR6129 →	+0.633	+3.496	<.001	.005	3	1
UCEC	MIR6133 →	+0.711	+3.982	<.001	.003	3	1
UCEC	RN7SL820P →	+0.353	+3.982	<.001	.003	3	1
LUAD	DEFB107B →	+0.123	+7.930	<.001	.008	3	1
LUAD	MBD3L4 →	+0.064	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration

KRTAP20-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP20-2 data types