Q-omics provides the consensus-scored MIR6129 profile across patient tissues and cancer cell-line models. MIR6129 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, MIR6129 is differentially expressed in 3, with the highest sampling consensus in LIHC. Additionally, MIR6129 RNA expression shows 6,481 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUAD, LIHC, and STAD as cancer lineages where MIR6129 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR6129 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR6129 survival associations across molecular data types. MIR6129 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR6129 RNA expression–survival associations across cancer types. High MIR6129 expression shows unfavorable associations in LUAD, KIRC, KIRP, OV and TGCT, but favorable associations in BLCA. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .009). Together, the overview and detailed table identify LUAD as the clearest survival context for MIR6129 RNA expression.
This table summarizes MIR6129 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR6129. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR6129 shows higher tumor expression in LIHC, BRCA and KIRP. The LIHC box plot shows higher MIR6129 RNA expression in tumor versus normal tissue (log2 FC = +0.487, t-test p = .018).
This table shows molecular features associated with MIR6129 in patient tissues and cancer cell lines. In patient samples, MIR6129 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
