Q-omics provides the consensus-scored DEFB107B profile across patient tissues and cancer cell-line models. DEFB107B expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in THCA. Additionally, DEFB107B RNA expression shows 1,414 significant pathway-activity associations, with the highest sampling consensus in KIRC. Together, these results highlight THCA, and KIRC as cancer lineages where DEFB107B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB107B survival associations across molecular data types. DEFB107B RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB107B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	THCA (36)	view →

This table ranks reproducible DEFB107B RNA expression–survival associations across cancer types. High DEFB107B expression shows unfavorable associations in THCA, KIRC, BRCA and GBM. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for DEFB107B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.062	0.909	<.001	36	view →
KIRC	DFS	Tertile	IV	0.110	0.626	<.001	36	view →
BRCA	DFS	Tertile	All	0.130	0.526	.018	24	view →
GBM	DFS	Tertile	All	0.031	0.257	<.001	18	view →

Pink = unfavorable, green = favorable. all 4 lineages →

DEFB107B-THCA (DFS)

Kaplan–Meier survival curve for DEFB107B RNA expression in THCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB107B in patient tissues and cancer cell lines. In patient samples, DEFB107B shows the broadest associations at the RNA and protein expression levels, with KIRC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	1,414	KIRC (1169)	view →
RNA	1,387	KIRP (589)	view →