Across TCGA pan-cancer cohorts, DEFB107B RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated DEFB107B data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DEFB107B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DEFB107B expression acts as an unfavorable survival marker.
KIRC, THCA, and BRCA are the cancer types where DEFB107B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.